Asia-Pacific Education and Research Association (APERA)
12-1 F., No. 129, Sec. 1, Fuxing S. Rd., Taipei Taiwan
Tel: + 886 2 2740 1498"
Stephen B. Ryan
Professor of Intercultural Communication Yamagata University, Japan
2014 International Congress on Chemical, Biological and Environmental Sciences (ICCBES)
Paper submission deadline extension: March 15, 2014
May 7-9, 2014 in Kyoto, Japan
Noted, since there's a long break in Japan (April 26-May 6), we had to send the conference program and proceedings to be printed and published early. Any requests for modifying the author’s information/abstract/full paper in the ICCBES program/proceedings are not accepted after April 9, 2014
201405 Kyoto Program.pdf
1.) 京都大阪奈良5日遊Tour proposal for participants from Taiwan
In response to a large number of requests from Taiwan participants, the Flying Master Travel proposed their tour plan to Kyoto, Japan. Detailed information can be found below. This is a non-profit service by the secretariat. If you have any questions, please contact the travel agent directly.
20140507-Kyoto Tour Proposal (3).pdf 報名截止:2014.03.21
2.)Recommended stay-list of hotel options near 2014 ICCBES conference venue, please refer to Hotel_Map_in_Kyoto.pdf
The conference is to offer scholars, professionals, academics and graduate students to present, share, and discuss their studies from various perspectives in the fields of Chemical, Biological and Environmental Sciences and so forth. All theoretical, empirical and practical papers or abstract from scholars and professionals in the above fields are all highly welcome.
Let us know how we can help you by e-mailing us at firstname.lastname@example.org
VISA Announcement from ICCBES
Please note ICCBES is not authorized to assist with the VISA process beyond providing the Notification of Acceptance Letter issued by the ICCBES Committee Board.
Should your application be denied, ICCBES cannot change the decision of the Japan Ministry of Foreign Affairs, nor will ICCBES engage in discussion or correspondence with the MOFA or the Embassy of Japan on behalf of the applicant. The registration fee cannot be refunded when the VISA application of individual being denied.
Abstract submission deadline
Notification of acceptance
Mar. 01, 2014
Full paper submission deadline
Mar. 20, 2014
Registration due date
Mar. 20, 2014
Elena V. Batrakova
University of North Carolina at Chapel Hill, USA
Carriers that Break Barriers
The ability to precisely upregulate genes in inflamed brain holds great therapeutic promise. Here we report a novel class of vectors, genetically modified macrophages that carry reporter and therapeutic genes to neural cells. Systemic administration of macrophages transfected ex vivo with a plasmid DNA (pDNA) encoding a potent antioxidant enzyme, catalase, produced month-long expression levels of catalase in the brain resulting in three-fold reductions in inflammation and complete neuroprotection in mouse models of Parkinson’s disease (PD). This resulted in significant improvements in motor functions in PD mice. Mechanistic studies revealed that transfected macrophages secreted extracellular vesicles, exosomes, packed with catalase genetic material, pDNA and mRNA, active catalase, and NF-kb, a transcription factor involved in the encoded gene expression. Exosomes efficiently transfer their contents to contiguous neurons resulting in de novo protein synthesis in target cells. Thus, genetically modified macrophages serve as a highly efficient system for reproduction, packaging, and targeted gene and drug delivery to treat inflammatory and neurodegenerative disorders.
* All accepted full papers will have opportunities to be recommended to publish in Bentham Science Publishers (eISBN: 978-1-60805-416-9, 2012), a major STM journal publisher of more than 200 open access journals.